网络首发:2018-07-19,
纸质出版:2018
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邢福威, 江竞舟, 胡晓亮, 等. 永久起搏器患者中QRS宽度与心房颤动的关系[J]. 中山大学学报(医学科学版), 2018,39(4).
XING Fu-wei, JIANG Jing-zhou, HU Xiao-liang, et al. Association between QRS Duration with Atrial Fibrillation in Patients with Permanent Pacemaker[J]. Journal of Sun Yat-sen University (Medical Sciences), 2018, 39(4).
【目的】探讨永久性起搏器患者的起搏QRS 波宽度(QRSd)与术后心房颤动(AF)发生的关系。 【方法】我们回顾收集了180例因完全性/进展性房室传导阻滞而行永久性起搏器植入术的患者。所有的患者都 是右室间隔部起搏。心电图在术前和术后都有记录。QRSd在部分胸前导联(V1,V4和V6)、I导联和AVF导联 都有测量,QRS波差值由术后起搏QRSd减去术前QRSd获得。【结果】AF发生在64(35.56%)例患者中。AF发生 组和没有AF 发生组间,术前的QRSd 相比没有统计学差异,但QRSd 差值在V4 导联(P=0.022)和V6 导联 (P=0.001)有统计学差异。COX比例风险模型提示V6导联的QRSd差值(P=0.005,HR 1.822,95%CI 1.174-2.718, QRSd的间隔区值定为40 ms)和左心房直径(P=0.045,HR 1.042,95%CI 1.001-1.086)是预测AF发生的独立危 险因素。ROC曲线提示V6导联的QRSd差值可以预测AF的发生,尤其是术前QRSd较长的患者(≥120 ms,曲线 下面积为0.826,95%CI 0.685-0.967)。【结论】V6导联的QRSd差值与术后AF的发生可能存在正相关关系。
【Objective】To explore the association between paced QRS duration(QRSd)and the occurrence of atrial fibrillation(AF)in the patients with permanent pacemaker.【Methods】We selected 180 consecutive patients underwent pacemaker implantation for complete/advanced atrioventricular block. All of patients were paced from the right ventricular septum. Electrocardiography recordings were obtained at the beginning and the end of pacemaker implantation. QRSd was measured in precordial leads(V1,V4 and V6),I lead and AVF lead. The change value of QRSd was calculated by subtracting the pre-implantation QRSd from the post-implantation QRSd.【Results】The occurrence of AF was observed in 64(35.56%)patients. No significant differences in pre-implantation QRSd were observed between the AF occurrence and non-occurrence groups. The change value of QRSd in leads V4(P=0.022),and V6(P=0.001)differed significantly between the occurrence and non-occurrence groups. Cox??s proportional hazard model suggested that change value of QRSd in lead V6(P=0.005,HR 1.822,95%CI 1.174-2.718,interval scale of QRSd was 40 ms)and left atrial diameter (P=0.045,HR 1.042,95%CI 1.001-1.086)were independent risk factors for AF occurrence. Receiver operating charac? teristic curve suggested that change value of QRSd in lead V6 could predict AF occurrence,especially for patients with long pre-implantation QRSd(≥ 120 ms,area under the curve was 0.826,95%CI 0.685-0.967).【Conclusions】Change value of QRSd in lead V6 seems to be positive correlated with post-implantation AF occurrence.
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