【Objective】To investigate the association between dietary glycemic load (GL) and diabetes mellitus incidence among middle-aged and elderly adults in Guangzhou

China. 【Methods】Study population were Guangzhou community residents

who had twice participated in epidemiological investigations of type 2 diabetes mellitus which were conducted in Sun Yat-Sen Memorial Hospital in 2011 and 2013

aged 40-79 years

and were not newly or previously diagnosed as diabetes mellitus in 2011. Resurvey was conducted in 2015. Non-conditional logistic regression was used to investigate association between dietary GL and diabetes mellitus. 【Results】 During 2011~2015

102 of 768 participants were diagnosed diabetes mellitus and the cumulative rate was 13.3%. Participants were categorized into 4 groups according to quartiles of energy-adjusted GL. The multivariable-adjusted odds ratios across quartiles of energy-adjusted GL was 1.00

0.96

1.83

2.11 (95%CI

1.09-4.07) (P for trend < 0.01).【Conclusion】Among middle-aged and elderly people in Guangzhou

China

dietary GL may be one of the most important dietary factors affecting the incidence of diabetes mellitus. Reducing dietary GL might be helpful for the prevention of diabetes.