【Objective】To investigate the clinical characteristics and blood transfusion status of patients of liver cirrhosis and analyze its rationality.【Methods】We designed questionnaires to collect the data of patients admitted with liver cirrhosis including clinical features，blood transfusion，smoking，drinking and other living habits. We follow up the patients and analyze the blood transfusion rationality.【Results】Data on 198 patients was collected.34.8%（69/198）of all patients were transfused at least one blood component. Total blood transfusion was 371 times，of which 52.2% of the blood transfusion cases（36/69）were transfused with two or more blood during hospitalization. Among the 69 cases of blood transfusion，11 cases were treated with the first blood transfusion for the purpose of treatment and 58 cases for prevention.18 of those cases were infused with red blood cells of 90.5 units. 54.55 % （60/110）and 60.91%（67/110）of patients who had a pre-transfusion INR>1.3 did not receive plasma. 2.27%（2/88）of patients who had a pre-transfusion INR≤1.3 received plasma. 29.41%（5/17）who had a pre-transfusion fib≤1.0 received cryoprecipitate. 3.87% （7/181）who had a pre-transfusion fib>1.0 received cryoprecipitate.【Conclusions】Blood transfusion is common in patients with liver cirrhosis. Empirical and preventive blood transfusion is common also. We should take a more scientific restrictive blood transfusion strategy.