【Objective】To investigate the value of deep common iliac region lymphadenectomy in treatment of uterine malignancies.【Methods】88 patients with deep common iliac region lymphadenectomy in Third affiliated hospital of sun yat-sen university from March 2016 to June 2017 were enrolled in this study. The number of removed lymph nodes、metastatic lymph nodes、operative complication and so on were analyzed.【Results】The number of pelvic lymph nodes resection is from 18 to 52，the average is 26；the number of deep common iliac region lymph nodes resection is from 2 to 16，the average is 5. The number of pelvic lymph node metastasis is 11 and the rate is 12.5%；the number of deep common iliac region lymph node metastasis is 3，accounting for 27.3% of the total number of pelvic lymph node metasta? sis，which alone deep common iliac region lymph node positive in 1 case，9.0% of the total number of pelvic lymph node metastasis. The average operation time of single pelvic lymph node resection was 43 min and that of single deep common iliac region lymph nodes was 10 min. There was no severe complication.【Conclusion】Deep common iliac region lymphad? enectomy is feasibility and safety，27%of patients with pelvic lymph node metastasis has positive deep common iliac region lymph nodes，and we believe that the promotion and application of deep common iliac region lymphadenectomy can further improve the therapeutic effect of uterine malignancy.