Abstract: 【Objective】 To investigate the correlation between the clinical variables and the 3-year survival rate of patients with prostate cancer. 【Methods】 The clinical data of 341 patients with prostate cancer were collected and analyzed. The 3-year survival rate was calculated. The correlation between 3-year survival rate and age (AGE)

total prostate specific antigen (TPSA)

digital rectal examination (DRE)

transrectal ultrasound (TRUS)

total prostate specific antigen(TPSA)

prostate specific antigen density (PSAD)

prostate specific antigen density of transition zone(PSATZ)

tumor stage(TNM)

metastasis

Gleason score

treatments were analyzed by one-way ANOVA and logistic regression analysis. The cutoff value

sensitivity and specificity of the independent correlation factors were calculated. 【Results】 The 3-year survival rate and disease-specific survival rate of 341 prostate cancer patients were 57.4% and 60.7%

respectively. Tumor staging

metastasis

Gleason score and treatments were correlated to 3-year survival (P < 0.05)

whereas Gleason score and treatment were independent correlation factors of 3-year survival by logistic regression analysis. The cutoff value of Gleason Score was 7.5. The sensitivity and specificity of Gleason Score were 35.8% and 75.3%

respectively. 【Conclusion】 Gleason score and treatment arepredictive factors of 3-year survival in patients with prostate cancer. Higher Gleason score or no treatments cause less 3-year survival.