Short -term Effects of Nutriment for Renal Disease in Nondialyzed Patients with Chronic Renal Insufficiency[J]. Journal of Sun Yat-sen University (Medical Sciences), 2016, 37(3).
Short -term Effects of Nutriment for Renal Disease in Nondialyzed Patients with Chronic Renal Insufficiency[J]. Journal of Sun Yat-sen University (Medical Sciences), 2016, 37(3).DOI:
Abstract: 【Objective】 To investigate short–term effects of nutriment for renal disease on nutritional status and calcium–phosphorus metabolism in nondialyzed patients with chronic renal insufficiency. 【Methods】 59 in -patients with CKD stages 3 -4 were divided into intervention group (29 patients) and control group (30 patients) randomly. Two groups were both supplied individual nutritional counseling. Intervention group was given nutriment for renal disease (60 g
tid) for 10 to 30 days. The parameters of nutritional status
calcium–phosphorus metabolism and renal function were measured on baseline and after interventions. 【Results】 Mean time of intervention in intervention group and control group were 15 ± 5 days and 15 ± 4 days
respectively. Phosphorus level significantly decreased after intervention in intervention group (ΔP = -0.14 ± 0.28 mmol/L
P = 0.014) and it was significantly different from control group (P = 0.038). Total protein level had no significant change after intervention in intervention group (P > 0.05) but significantly decreased in control group (P < 0.05) and the difference of this change between two group was significant (intervention group (-0.56 ± 5.26)g/L; control group (-3.69 ± 6.12)g/L; P = 0.040). Renal function had no significant change after intervention in both two groups (P > 0.05). 【Conclusions】 Short -term supplement of nutriment for renal disease in nondialyzed patients with chronic renal insufficiency was useful for improvement of calcium–phosphorus disorder and protein wasting status without significant impact on renal function.