【Objective】 To investigate the prevalence of metabolic syndrome in obese children and adolescents and the clinical characteristic in outpatient. 【Method】 According to the newest diagnosis criteria of metabolic syndrome in children in china

the databases of the clinical and experimental characteristics in simple obesity children and adolescents diagnosed from 2008 to 2011 in the First Affiliated Hospital of SUN Yat-sen University were analyzed. 【Results】 119 patients with simple obesity were enrolled in the study

all were above 6 years old. 51(42.86%) had at least one component of metabolic syndrome

47(39.50%) had two components. 21(17.65%) had more than two components of metabolic syndrome. Triglyceride (TG)

non-high-density lipoprotein cholesterol (nonHDLC) and homeostasis model assessment-insulin resistance index (HOMA-IR) in three and over components of metabolic syndrome group were significant higher than these of the other groups (P < 0.05). The three groups all were central obesity. Correlation analysis suggests that the level of nonHDLC was positively related with total cholesterol (TC)

low density lipoprotein cholesterin (LDC-C)

TG and the number of metabolic syndrome component. Non-alcoholic fatty liver disease (NAFLD) was positively related with FINS and HOMA-IR. 【Conclusions】Obese children in outpatient have high prevalence of the metabolic syndrome. Central obesity (CO) may be the initiating factor of metabolic abnormality. NonHDLC was the main dyslipidemia. Insulin resistance

hypreinsulinemia were the main factors causing NAFLD.