Abstract: 【Objective】 To investigate the pregnancy outcomes of patients who have low number of total progressively motile sperm count (TPMSC) post wash in intrauterine insemination (IUI) cycles. 【Methods】 1056 IUI cycles with TPMSC< 10.0 ×106 were included and their pregnancy outcomes were retrospectively analyzed. To further study the relationship between TPMSC and pregnancy rate

cycles with low number of TPMSC(× 106) were divided into four groups; 0.1 ~ < 0.5

0.5 ~ <1.0

1.0 ~ < 5.0

5.0 ~ < 10.0

the pregnancy rates were compared among these groups. 【Results】 1 056 IUI cycles with TPMSC < 10.0 × 106 were included in the present study got an overall pregnancy rate of 12.3%

the miscarriage rate was 16.2% and the live birth rates was 83.9%.The patients who have post washed TPMSC < 0.1 × 106 failed to obtain a pregnancy. For patients with low number of TPMSC post wash (0.1 × 106≤TPMSC< 10.0 × 106)

the pregnancy rates per cycle were 14.4%

10.6%

12.5%

and 12.0%

respectively in four groups with no statistical difference. After Logistic regression analysis

the pregnancy rates of patients with low number of TPMSC post wash were influenced by female ages

infertility factors and duration time of infertility. TPMSC post wash was not related with pregnancy rates.【Conclusions】 Patients with low number of total progressively motile sperm count post wash (0.1 × 106 ≤ TPMSC < 10.0 × 106) can still get satisfactory rates of pregnancy through IUI treatment

but TPMSC and pregnancy rate were not correlated within this TPMSC range.