Whole Course 225 U Recombinant Luteinizing Hormone Application can Decrease Serum Vascular Endothelial Growth Factor Level on Oocyte Pick Up and Embryo Transfer Day
Whole Course 225 U Recombinant Luteinizing Hormone Application can Decrease Serum Vascular Endothelial Growth Factor Level on Oocyte Pick Up and Embryo Transfer Day[J]. Journal of Sun Yat-sen University (Medical Sciences), 2015, 36(2).
Whole Course 225 U Recombinant Luteinizing Hormone Application can Decrease Serum Vascular Endothelial Growth Factor Level on Oocyte Pick Up and Embryo Transfer Day[J]. Journal of Sun Yat-sen University (Medical Sciences), 2015, 36(2).DOI:
【Objective】 To investigate the effectiveness of luteinizing hormone (LH) in decreasing serum vascular endothelial growth factor (VEGF) level during controlled ovarian hyperstimulation (COH). 【Method】 Comparing serum VEGF level on COH starting day and comparing elevated serum VEGF level on human chorionic gonadotropin (HCG) administration day
oocyte pick up (OPU) day and embryo transfer (ET) day between 20 patients with whole course 225 U LH application and 50 patients without during COH. 【Results】 Serum VEGF level on starting day and serum VEGF level elevated on HCG day was comparable of two groups. However
serum VEGF level elevated on OPU day (P = 0.017) and ET day (P = 0.009) of study group were significantly lower than control group. 【Conclusion】 Whole course 225 U LH application during COH can effectively decrease serum VEGF level on OPU and ET day.