Abstract: 【Objectives】 To evaluate the value of spectral CT quantitative indicators in the differential diagnosis of metastatic and non-metastatic lymph node in NSCLC. 【Methods】 48 patients with NSCLC were enrolled including metastatic lymph nodes group (n=34) and non-metastatic lymph nodes group (n = 40). Unenhanced

arterial phase and venous phase enhanced spectral CT quantitative indicators were compared between metastatic and non-metastatic lymph nodes. 【Results】 Iodine Concentrations

effective Z value

normalized effective Z value of metastatic lymph node group were statistically lower than that of non-metastatic lymph node group both in unenhanced phase and in arterial phase

same result was found as well as normalized Iodine Concentrations in arterial phase (P 0.1574 as criteria to get a diagnosis of non-metastatic lymph node was 86.7%. 【Conclusions】 Spectral CT quantitative indicators can provide quantitative analysis in differential diagnosis of metastatic and non- metastatic lymph node in NSCLC

and improving the diagnostic accuracy of N staging of NSCLC.