【Objective】 To explore if the serum AHSG level of women during early and mid gestation can anticipate the level of blood glucose in the late trimester pregnancy and make the pregnancy outcome abnormal

then a forecast system of gestational diabetes mellitus and complications can be established

at the same time

the national differences will be discussed. 【Methods】 Retrospective study was used for the 776 women (gestational weeks: 3841) who were divided into two groups according to the nationality. The relationship between the blood glucose in the late trimester pregnancy and the pregnancy outcome was investigated firstly. Database were established which included the following fundamental states: age

nationality

FBG

HbAlc

pregnancy outcome

and BMI. Ninty samples (7-22 weeks) were detected the serum AHSG level. Enzymelinked immunosorbent assay was used in the detection. The pregnant outcomes of 16 samples were not available

74 were absorbed in the terminal study

the association amony the serum AHSG level

blood glucose and the pregnancy outcome were analyzed

the ethnic differences would also be discussed.【Results】 The high level FBG before the pregnant can result in adverse pregnancy outcomes (P < 0.05)

the AHSG level correlated significantly with pregnancy outcome (r = -0.238

P = 0.014). However

there was no ethnic differences between them.【Conclusion】 Adverse pregnancy outcomes can be induced by high level glucose

there was no ethnic differences

the AHSG level correlated significantly with pregnancy outcome but not with FBG

so we cannot draw a conclusion that the AHSG can result in Adverse pregnancy outcomes by changing the glucose level. However

AHSG can be used as a forecast factor of pregnant outcome.