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息肉样脉络膜血管病变的频域光相干断层扫描图像特征分析[J]. 中山大学学报(医学科学版), 2012,33(6).
Main Features of Polypoidal Choroidal Vasculopathy by Spectral-domainOptical Coherence Tomography[J]. Journal of Sun Yat-sen University (Medical Sciences), 2012, 33(6).
【目的】 研究息肉样脉络膜血管病变(PCV)的频域光相干断层扫描图像(SD-OCT)特征并分析其临床意义。【方法】 对经眼底检查、眼底彩照、荧光素血管造影和吲哚青绿造影确诊的连续PCV患者的SD-OCT图像进行分析,分析PCV在SD-OCT上的主要表现形式。【结果】 共95例患者(106眼)纳入该研究,其中18眼(16.98%)出现广泛性出血性色素上皮层脱离(mhPED)伴或不伴视网膜下大出血(MSH),总范围大于12个视盘面积;在无mhPED/MSH的98眼中,78眼(79.59%)可见双线征,71眼(72.45%)见局限性视网膜色素上皮脱离,42眼(42.86%)见拇指样隆起息肉病变,65眼(66.33%)见视网膜下积液,20眼(20.41%)见视网膜层间积液,29 (29.59%) 眼见局限性视网膜下出血。【结论】 双线征、色素上皮脱离、视网膜下积液、拇指样息肉病灶以及视网膜下出血是PCV在SD-OCT上常见的5种表现形式,其中以双眼线征和色素上皮脱离最为常见。
【Objective】 To investigate the spectral-domain optical coherence tomography (SD-OCT) findings in eyes with polypoidal choroidal vasculopathy (PCV). 【Methods】 This observation recruited 106 eyes of 95 PCV patients confirmed by fundus photography, fundus fluorescein angiography (FFA) and indocyanine green angiography (ICGA). Main manifestations and signs on OCT were analyzed. 【Results】 Massive hemorrhagic pigment epithelial detachment (mhPED) with/without massive subretinal hemorrhage (MSH) was shown in 18 of 106 eyes (16.98%) with PCV on SD-OCT. In the 98 eyes without mhPED/MSH, double-layer sign (DLS) was detected in 78 eyes (79.59%), local pigment epithelial detachment (PED) was present in 71 eyes (72.45%), 42 eyes (42.86%) had thumb-like polyps (TLP), subretinal fluid (SRF) and intra-retinal fluid (IRF) were seen in 65 eyes (66.33%) and 20 eyes (20.41%) respectively, local subretinal hemorrhage (SRH) was detected in 29 eyes (29.59%). 【Conclusion】DLS, PED, TLP, SRF, and SRH, are the main OCT signs of PCV on SD-OCT, while DLS and PED are the most common ones.
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