【Objective】 To explore the polymorphic distribution of 30 Indel loci included in Investigator R DIPplex system and evaluate its potential forensic application in Guangdong Han population. 【Methods】 DNA samples were extracted from 300 unrelated individuals (150 males and 150 females) and 30 Indel loci were multiamplified with Investigator R DIPplex kit. The PCR products were separated with arrayed capillary electrophoresis and genotyped with GeneMapper IDX v1.2 software. Forensic parameters were calculated with relevant statistical analysis software. 【Results】 All the 30 loci showed no significant departure from HardyWeinberg equilibrium or linkage disequilibrium after Bonferroni＇s correction. The average heterozygosity (Ho) was 0.406

the mean discrimination power (DP) was 0.549

the mean polymorphism information content (PIC) was 0.320

the combined discrimination power (TDP) reached 0.999 999 999 98. The combined power of exclusion was 0.994 748 in trio cases (CPEtri) and 0.942 342 in duo cases (CPEduo). 【Conclusion】 The 30 loci denotes good genetic diversity in Guangdong Han population

which could be used for individual identification independently and be used as a supplemental tool for some special paternity testing cases when STR mutated.