【Objective】 To explore the survival difference following mitral valve replacement vs mitral valve repair in the patients with ischemic mitral valve regurgitation through metaanalysis.【Methods】 PubMed

Cochrane Library

EMbase

CNKI

CBM and other online database were searched

and some journals manually searched to collect published or grey literatures of clinical researches on all literatures about surgery treatment of ischemic mitral valve regurgitation (direct comparison of replacement vs repair)

and screened for metaanalyzing the shortterm and longterm mortality following mitral valve replacement vs mitral valve repair. 【Results】 Thirteen articles in total finally entered into the metaanalysis. These studies owning the similar general patient preoperative characteristics

mean EF and proportion of severe left ventricular dysfunction. The shortterm mortality (inhospital mortality) of the mitral valve replacement group was higher than that of the mitral valve repair group

OR = 1.92 (95% CI 1.37-2.21)

no significant difference was found for longterm mortality between the two groups

OR = 1.20 (95% CI 0.951.5).【Conclusion】 The shortterm survival was better in the mitral valve repair group for ischemic mitral valve regurgitation comparing to the mitral valve replacement group

no significant difference was found in longterm survival.