【Objective】To analyze the clinical outcome of the severe intrauterine adhesions

to investigate clinical efficacy of severe IUA with transcervical resection and artificial cycle treatment. 【Methods】 A total of 72 cases which diagnosed severe intrauterine adhesion (44 cases with degree-IV intrauterine adhesions

the other 28 with degree V) were collected in our research. After transcervical resection of adhesions

we followed-up the IUA patients to investigate the safety and efficacy of 9 mg/d estrogen artificial cycle. 【Result】 9 mg/d estrogen artificial cycle after surgery was safe and effective for IUA patients. After post-operation artificial cycle treatment the IUA endometrium were thicker

but still not satisfactory. The treatment of intrauterine adhesion improves reproductive outcome obviously

which depends on the nature

degree and scope of adhesions.