【Objective】 The purpose of our study was to determine possible factors associated with parametrial spread in the patients with stage IB1 cervical cancer and define parameters associated a low risk for parametrial spread

in order to identify candidates for less radical surgery. 【Methods】 We retrospectively reviewed 149 patients with stage IB1 cervical cancer who had undergone primary radical hysterectomy (class III) and pelvic lymphadenectomy in our department from January 2008 to February 2011. All clinical pathological parameters including parametrial involvement were statistically analyzed in SPSS 18.0

with univariate χ2test and multivariate logistic regression model. 【Results】 Overall

8 (5.4%) of the 149 patients revealed parametrial spread. Tumor size

lymph vascular space invasion (LVSI)

positive lymph nodes

depth of invasion

vaginal spread and uterine metastasis were significantly associated with parametrial involvement (P < 0.05). The multivariate analysis model showed positive lymph nodes (HR: 26.95

95%CI: 2.32-313.41) and LVSI (HR: 47.6

95% CI: 2.561-886.32) to be the independent predictors of parametrial spread. In patients with no LVSI and negative pelvic nodes

parametrial involvement was found to be 0.0% (0/88). 【Conclusion】Patients with stage IB1 cervical cancer have a relatively lower risk for parametrial spread. Those who without positive lymph nodes or LVSI could be considered for less radical surgery such as modified radical hysterectomy or simple hysterectomy with pelvic lymphadenectomy. Furthermore

postoperative complications including vesical dysfunction and anorectal mobility disorders could be reduced as a result

it will be confirmed by randomized clinical trait of large sample.