【Objective】 To determine the predictive value of the endometriosis fertility index and rAFS classification for the outcome of cumulative pregnancy in IVF cycles. 【Method】 Totally 109 infertile women with 143 IVF cycles were retrospectively analyzed from January 2008 to December 2011. Before IVF cycle

these women were diagnosed as endometriosis and treated by laparoscopy in our hospital. Medical history

surgery materials

and pregnancy outcome were collected. Staged patients according to the revised American Fertility Society System; calculated EFI score basing on the endometriosis fertility index system; the ROC curve and the multilevel statistical models were used to assess the differences in cumulative pregnancy rates between different EFI scores and rAFS stages. 【Result】 (1) The areas under ROC curve (AUC) of EFI and rAFS were 0.644 (P < 0.05) and 0.415 (P > 0.05)

respectively. The best point for diagnosis by EFI was 6

so we use EFI scores of 6 as the point. The accumulative pregnancy rates of a EFI scores of 4 (n = 26) and 5 (n = 28) were 40.0% and 44.5%

respectively

there were no significant differences (P > 0.05). The total cumulative pregnancy rates among patients with EFI scores of ≥6 were significantly higher than that of EFI score of ≤5 (38.2% vs 60.6%

P = 0.005). The accumulative pregnancy rates among the EFI scores of 6 (n = 36) and ≥7(n = 37) were comparable (61.8% vs 59.5%

P > 0.05). But the EFI scores of <3

have only 17 IVF cycles

the cumulative pregnancy rate was 25.0%. 28

12

39

64 IVF cycles were assigned to stage Ⅰ

Ⅱ

Ⅲ

and Ⅳ according to the revised American Fertility Society System

statistical significance was not achieved in accumulative pregnancy rates among all stages (Ⅰ ~ Ⅳ

P = 0.163). 【Conclusion】 EFI can be used as a good effective tool to predict pregnancy outcome in the patients attempted to IVF after laparoscopic surgery

the cumulative pregnancy rates among EFI scores of ≥6 were obviously increased

which provides an important basis for IVF treatment. The predictive value of rAFS classification for the pregnancy outcome in IVF cycles were not found.