【Objective】 The aim of this study was to evaluate the clinical value of combined preoperative endoscopic ultrasound (EUS) and laparoscopic ultrasound (LUS) for prediction of surgical resectability in the patients with pancreatic carcinoma. 【Methods】 From March 2006 to October 2009

56 patients diagnosed with pancreatic carcinoma were entered into this study. Patients were first examined with EUS followed by LUS

if EUS did not find any signs of non-resectability. 【Results】 Only patients with tumors found to be possibly resectable at EUS and LUS were offered exploratory operation. And the allocation of patients into possible resectability group by EUS and LUS were compared with the radical resection actually undertaken. In all

radical resection could be undertaken in only 35.7% patients. 91.7% cases with non-resectable tumor avoided futile explorations because of EUS and LUS.The specificity

accuracy

and positive predictive value of EUS and LUS in identifying resectability was 63.9%

76.8%

60.6%

and 76.9%

90.3%

85.7%

respectively. But combined EUS and LUS improved the specificity and accuracy to 91.7% and 94.4%.【Conclusion】 As a conclusion

combined EUS and LUS has a high predictive value for resectability in patients with pancreatic carcinoma and helps to reduce the number of futile explorations.