【Objective】 To assess the feasibility of individual-adapted tube current-time scanning protocol for multiple detector row computed tomography pulmonary angiography (MDCTPA). 【Methods】 Ninety patients with suspected pulmonary embolism (PE) accepted MDCTPA examination. All patients were randomized divided into 6 groups (15 each). Objective and subjective image quality and effective dose (ED) were assessed and compared in these groups. 【Results】 The differences of subjective image quality scores and Effective dose (ED) in these 6 groups were significantly different(P = 0.008

P < 0.01

respectively). There were no significant differences between group C and group F in objective/subjective parameters. The mean value of ED in group C was reduced by 47.8% than group F. 【Conclusion】 An individually adapted scanning protocol of MDCTPA using tube current-time based on patient’s body weight could be effectively performed in clinical setting. With the tube current-time of 1.0 mA﹒/kg

balance between the image quality and reduction of radiation exposure could be achieved.