Effect of Adoptive Immunotherapy with Auto-cytokine Induced Killer Cells on Tumor Markers and General Condition of Patients with Nasopharyngeal Carcinoma
Effect of Adoptive Immunotherapy with Auto-cytokine Induced Killer Cells on Tumor Markers and General Condition of Patients with Nasopharyngeal Carcinoma[J]. Journal of Sun Yat-sen University (Medical Sciences), 2011, 32(4).
Effect of Adoptive Immunotherapy with Auto-cytokine Induced Killer Cells on Tumor Markers and General Condition of Patients with Nasopharyngeal Carcinoma[J]. Journal of Sun Yat-sen University (Medical Sciences), 2011, 32(4).DOI:
【Objective】 To investigate the remission of the symptom and the antibodies of EB virus after the CIK cells being transfused back to the patients with nasopharyngeal cancer. 【Methods】 42 cases were enrolled
and 21 patients (group A) received not only chemotherapy and radiotherapy but also adoptive immunotherapy with auto-cytokine induced killer cells compared with the other 21 patients (group B) who only accepted radiotherapy and chemotherapy. 【Result】 During the following 6-27 months (median: 14.5 months)
the antibodies of VCA-IgA
EA-IgA
EA-IgG
and EVB-DNA in group A were all lower than that in group B. And also was the appetite. But in group A
the efficiency of treatment was not improved compared with group B. 【Conclusion】 Adoptive immunotherapy with auto-cytokine induced killer cells is safe and effective in clinical
and it can degrade VCA-IgA
EA-IgA
EA-IgG
and EBV-DNA which are increased in the patients with nasopharyngeal cancer
and it also improve the quality of living of the patients. But it did not improved the treatment efficiently.