Relationship between Risk Factors of GDM and Postpartum Early Abnormal Glucose Regulation[J]. Journal of Sun Yat-sen University (Medical Sciences), 2011, 32(6).
Relationship between Risk Factors of GDM and Postpartum Early Abnormal Glucose Regulation[J]. Journal of Sun Yat-sen University (Medical Sciences), 2011, 32(6).DOI:
【Objective】 To investigate the relationship between traditional risk factors of gestational diabetes mellitus (GDM) and pregnancy outcome as well as postpartum early abnormal glucose regulation. 【Methods】 Risk factors or 50 g oral glucose tolerance test (OGTT) were used to scan GDM in 3017 pregnant women
the 75 g OGTT were performed to confirm the diagnosis of GDM in those with positive results. GDM women were divided into two groups: women with risk factors (n = 143) and without risk factors (n = 175). All GDM women were recruited to take 75 g OGTT at 6-8 weeks and 6-12 months after delivery. 【Results】 Total 318 GDM were confirmed in those 3017 pregnant women. The prevalence of GDM in women with risk factors were higher than those without risk factors (41.81% vs 6.54%
P < 0.01). Additionally
compare to those without risk factors
women with risk factors has higher pregnant complications
higher premature birth rate
and birth-weight. Also a higher incidence of early postpartum abnormal glucose tolerance was observed in those with GDM risk factors. Logistic regression analysis indicated that family history of diabetes and positive uric glucose were relative to the early postpartum abnormal glucose tolerance. 【Conclusions】 The GDM risk factors are not only the predictor of GDM
but also are relative to postpartum early abnormal glucose regulation. Among these risk factors
family history of diabetes and positive uric glucose are of greater contribution.