【Objective】This study w as performed to evaluate the blood glucose reduction effect of an acute exercise loading o n non-insulin-dependent diabetes mellitus (NIDDM)patient s at different time af ter meal . 【Methods】Eighteen non-insulin-dependent diabetic patients had been chosen to be loaded with 30 minutes acute exercise

60 %VO2max in intensity

w hich w as performed 30 minutes

60 minutes and 90 minutes af ter meal in three ex perimental day s respectively .The day w ithout exercise loading had been taken as cont rol .The blood g lucose concent ration was assayed at 30

60

90

120

150

180

210 minutes after meal.【Results】A signif icant decrease the g lucose-time curve areas (21.3 mmol·h·L -1 ±4.4 mmol·h·L -1 vs 25.4 mmol·h·L -1 ±5.1 mmol ·h·L -1

P <0.05)

the glucose levels at the end of acute exercise(5.4 mmol·L -1 ±1.4 mmol·L -1 vs 8.2 mmol·L -1 ±1.8mmol·L -1

P <0.01)and the glucose concentration at30

60

90 minutes af ter meal by acute exercise at 90 min af ter meal .Acute exercise at 60 min af ter meal sig nificant ly decrease the glucose level at the end of acute exercise(6.8 mmol·L -1 ±1.7 mmol·L -1 vs 8.3 mmol·L -1 ±2.1mmol·L -1).There w ere no signif icant changes observed in blood g lucose in acute exercise at 30 min af ter meal.【Conclusion】The data suggest that exercise at 90 min af ter meal is most helpful to lower blood glucose .