LI-RADS与亚洲肿瘤峰会标准对小肝癌的诊断效能分析

王影; 余深平

您当前的位置：

首页 >

文章列表页 >

LI-RADS与亚洲肿瘤峰会标准对小肝癌的诊断效能分析

更新时间：2023-12-12

- LI-RADS与亚洲肿瘤峰会标准对小肝癌的诊断效能分析
- Comparison of Diagnositic Efficiency between LI-RADS（v2013）and AOS Clinical Guideline for Diagnosis of Small Hepatocellular Carcinoma
- 中山大学学报（医学科学版） 2019年40卷第3期
- 作者机构：
  
  1. 中国科学技术大学附属第一医院影像科,安徽,合肥,230000
  2. 中山大学附属第一医院放射科,广东,广州,510080
- 作者简介：
- 基金信息：
  
  广东省科技计划项目（2014A020212126）
- DOI：
  中图分类号： R735.7
- 网络首发：2019-05-14，
  
  纸质出版：2019
- 稿件说明：
移动端阅览
王影, 余深平. LI-RADS与亚洲肿瘤峰会标准对小肝癌的诊断效能分析[J]. 中山大学学报（医学科学版）, 2019,40(3).

Comparison of Diagnositic Efficiency between LI-RADS（v2013）and AOS Clinical Guideline for Diagnosis of Small Hepatocellular Carcinoma[J]. Journal of Sun Yat-sen University (Medical Sciences), 2019, 40(3).
王影, 余深平. LI-RADS与亚洲肿瘤峰会标准对小肝癌的诊断效能分析[J]. 中山大学学报（医学科学版）, 2019,40(3). DOI：

Comparison of Diagnositic Efficiency between LI-RADS（v2013）and AOS Clinical Guideline for Diagnosis of Small Hepatocellular Carcinoma[J]. Journal of Sun Yat-sen University (Medical Sciences), 2019, 40(3). DOI：

摘要

【目的】比较肝脏影像报告和数据管理系统LI-RADS（v2013）和亚洲肿瘤峰会AOS标准对小肝癌的诊断价值。【方法】回顾性分析有肝细胞癌发病风险的220名共289处直径≤30mm和106名共129处直径<20mm的肝脏病变的CT、MRI征象，分别依据LI-RADS（v2013）和AOS临床实践指南提出的影像学诊断标准，比较两者的敏感度、特异度、阳性预测值、阴性预测值及两者ROC曲线下面积（AUC值），以此评估二者的诊断价值。【结果】①直径≤30mm者，LI-RADS（v2013）对小肝癌的敏感度、特异度、阳性预测值和阴性预测值分别为100%、67.53%、72.97%、100%，LR3-5级的阳性预测值分别为50%、73.02%、91.18%；AOS对小肝癌的敏感度、特异度、阳性预测值和阴性预测值分别为54.81%、92.21%、86.05%、70%；LI-RADS（v2013）、AOS的AUC值分别为0.83、0.74。②直径<20mm者，LI-RADS（v2013）对小肝癌的敏感度、特异度、阳性预测值和阴性预测值分别为100%、73.56%、64.62%、100%，LR3-5级的阳性预测值分别为56.67%、83.33%、63.64%；AOS对小肝癌的敏感度、特异度、阳性预测值和阴性预测值分别为42.86%、93.10%、75%、64.80%；LI-RADS（v2013）、AOS的AUC值分别为0.87、0.68。【结论】对于直径≤30mm和<20mm的小肝癌，LI-RADS（v2013）的诊断价值高于AOS，其敏感度明显高于AOS、特异度较AOS略低，但LI-RADS（v2013）针对不同级别的处理原则可在一定程度上避免过度医疗。

Abstract

【Objective】 To discuss the diagnostic value of LI- RADS（v2013） and the criteria proposed by AOS clinical guideline for small hepatocellular carcinoma. 【Methods】This retrospective trial included 289 liver lesions with diameter no more than 30 mm in 220 patients and 129 liver lesions diameter less than 20 mm in 106 patients. These patients all with chronic liver diseases had taken the examination of multi-layer spiral CT and/or high field MRI ，with pathology being the golden standard，to compare the diagnostic efficiency between LI-RADS（v2013）and AOS criteria， which included sensitivity ，specificity ，positive predictive value ，negative predictive value and their AUC values.【Results】① For lesions with diameter no more than 30 mm，the sensitivity，specificity，positive predictive value and negative predictive value of LI-RADS（v2013）for small hepatocellular carcinoma were 100%，67.53%，72.97%，100%，and the positive predictive value for score LR3 to LR5 in LI-RADS（v2013）were 50%，73.02% and 91.18% respectively， and the sensitivity，specificity，positive predictive value and negative predictive value of AOS criteria for small hepatocellular carcinoma were 54.81% ，92.21% ，86.05% ，70% respectively，and the AUC value of LI- RADS（v2013）and AOS were 0.83 ，0.74 respectively. ②For lesions diameter less than 20 mm，the sensitivity，specificity，positive predictive value and negative predictive value of LI- RADS（v2013）for small hepatocellular carcinoma were 100% ，73.56% ，64.62% ，100% ，and the positive predictive value for score LR3 to LR5 in LI-RADS（v2013）were 56.67%，83.33% and 63.64% respectively，and the sensitivity，specificity，positive predictive value and negative predictive value of AOS criteria for small hepatocellular carcinoma were 42.86%，93.10%，75% ，64.80% respectively，and the AUC value of LI- RADS（v2013） and AOS were 0.87，0.68 respectively.【Conclusions】The diagnostic value of LI-RADS（v2013）for small hepatocellular carcinoma was higher than AOS criteria. The sensitivity of LI- RADS（v2013）was much higher than AOS ，though the specificity was a little lower. However，the different treatment principles of LI-RADS（v2013）according to different scores can avoid excessive medical care，which can to a certain extent avoid the bad effect of its relatively lower specificity.

关键词

Keywords

references

浏览量

492

下载量

CSCD

文章被引用时，请邮件提醒。

提交

工具集

关联资源

胆囊神经内分泌肿瘤的CT与MRI影像学表现

卵巢甲状腺肿的影像学特征

多层螺旋CT分析周围型肺癌形态学特征—MPR正交重组切面结合MIP

CT心包新月征在非钙化的缩窄性心包炎的诊断价值

颞骨巨细胞修复性肉芽肿影像表现与手术和病理对照