Abstract:【Objective】 To assess the intra - and inter -observer repeatability of the evaluation of fetal cardiac structures and measurement from the volumes obtained by four -dimensional spatiotemporal image correlation (STIC) technology in first -trimester of pregnancy. 【Methods】 STIC volumes were obtained from 115 singleton pregnancies with normal fetal heart from February 2012 to June 2013 at gestational age of 11 to 13+6 weeks. Four standard cardiac views as well as ten measurements of the fetal heart were evaluated by two different reviewers respectively. The reliability of qualitative variables was evaluated using Cohen’s kappa while that of quantitative parameters was assessed using the intraclass correlation coefficient (ICC). 【Results】 Satisfactory scanning were considered in more than 85% of cases. The differences between gray -scale and color Doppler imaging were statistically significant in identifying three vessel view. Good or excellent intra - and inter -observer agreement (К > 0.82) was obtained for all four standard cardiac views. Regarding the quantitative cardiac measurements

ICC values were above 0.86 for 7/10 parameters. 【Conclusion】Cardiac examination from STIC volumes showed a high repeatability between and within observers in first -trimester. STIC technology for assessing first -trimester heart are feasible and repeatable.