中山大学附属第八医院妇科,广东 深圳 518000
付艳霞,第一作者,研究方向:妇科肿瘤,E-mail: fuyx2005@163.com
收稿:2026-06-10,
修回:2026-07-06,
录用:2026-07-07,
网络首发:2026-07-21,
纸质出版:2026-07-20
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付艳霞,李冬寒,程丽琴等.超声引导下微波消融治疗子宫动静脉瘘探讨[J].中山大学学报(医学科学版),2026,47(04):739-746.
FU Yanxia,LI Donghan,CHENG Liqin,et al.Ultrasound-guided Microwave Ablation for Uterine Arteriovenous Fistula[J].Journal of Sun Yat-sen University(Medical Sciences),2026,47(04):739-746.
付艳霞,李冬寒,程丽琴等.超声引导下微波消融治疗子宫动静脉瘘探讨[J].中山大学学报(医学科学版),2026,47(04):739-746. DOI: 10.11714/jsysu.med.YX20260079.
FU Yanxia,LI Donghan,CHENG Liqin,et al.Ultrasound-guided Microwave Ablation for Uterine Arteriovenous Fistula[J].Journal of Sun Yat-sen University(Medical Sciences),2026,47(04):739-746. DOI: 10.11714/jsysu.med.YX20260079.
目的
2
分析子宫动静脉瘘(UAVF)的临床表现、诊断、治疗方法及预后结局。
方法
2
回顾性分析2010年1月至2023年12月中山大学附属第八医院妇科收治的6例UAVF患者。总结这6例患者的临床资料,包括年龄、孕次、主诉、治疗方案及术后随访结果,并结合文献探讨超声引导下微波消融治疗UAVF的临床疗效及安全性。
结果
2
患者年龄26~44(34.33±6.12)岁,中位年龄33.5岁。所有患者均经彩色多普勒超声初筛诊断,并经子宫动脉造影、CT或MRI等影像学检查进一步确诊。患者既往妊娠史中位数为4(4, 6)次,其中5例有≥2次妊娠史;5例有宫腔操作史,其中4例有≥2次宫腔操作史。临床主诉方面,3例表现为异常阴道流血(其中2例为大出血);2例无明显症状,仅表现为影像学异常;1例表现为下腹痛。治疗方面,1例在子宫动脉栓塞(UAE)后复发,采用超声引导下微波消融治疗;1例单纯行UAE治疗;2例合并胚物残留者行宫腔镜下机械旋切术(其中1例术后10 h发生大出血,经球囊压迫止血成功);1例行病灶切除术;1例行全子宫切除术。6例患者治疗效果均满意。
结论
2
异常阴道流血是UAVF最典型的临床表现,子宫动脉数字减影血管造影为该病确诊金标准。合并急性大出血、血流动力学不稳定的患者需急诊实施UAE;对于UAE治疗失败或术后复发、且有保留子宫及生育需求的患者,超声引导下微波消融是一种安全有效的新型微创治疗手段。
Objective
2
To analyze the clinical manifestations, diagnostic approaches, treatment strategies, and prognostic outcomes of uterine arteriovenous fistula (UAVF).
Methods
2
We retrospectively analyzed 6 patients with confirmed UAVF admitted to the Department of Gynecology, the Eighth Affiliated Hospital of Sun Yat-sen University, between January 2010 and December 2023. We summarized the clinical data of the cohort, including age, gravidity, chief complaints, treatment regimens, and postoperative follow-up outcomes, and explored the clinical efficacy and safety of ultrasound-guided microwave ablation for UAVF in conjunction with a literature review.
Results
2
The patients were aged 26-44 years, with a mean age of (34.33±6.12) years and a median age of 33.5 years. All patients were initially screened via color Doppler ultrasound and definitively diagnosed by imaging modalities including uterine arteriography, computed tomography, and magnetic resonance imaging. The median gravidity was 4(4,6), with 5 patients having a history of ≥2 pregnancies. Five patients had a history of intrauterine instrumentation, among whom 4 had undergone ≥2 procedures. Regarding clinical presentations, 3 patients presented with abnormal vaginal bleeding (2 with massive hemorrhage), 2 were asymptomatic with abnormalities detected only on imaging, and 1 reported lower abdominal pain. In terms of management, 1 patient with recurrence after uterine artery embolization (UAE) underwent ultrasound-guided microwave ablation; 1 received UAE alone; 2 patients with concomitant retained products of conception underwent hysteroscopic mechanical morcellation (1 developed massive hemorrhage 10 hours postoperatively, which was successfully controlled with uterine balloon tamponade); 1 underwent focal lesion resection; and 1 underwent total hysterectomy. All 6 patients achieved favorable therapeutic outcomes.
Conclusion
2
Abnormal vaginal bleeding is the most typical clinical manifestation of UAVF, and digital subtraction angiography of the uterine arteries is recognized as the gold standard for definitive diagnosis. Emergency UAE is indicated for patients presenting with acute massive hemorrhage and hemodynamic instability. For patients with failed UAE or post-UAE recurrence who desire uterine and fertility preservation, ultrasound-guided microwave ablation represents a safe, effective, and novel minimally invasive therapeutic option.
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