上海交通大学医学院附属仁济医院泌尿男科,上海 200001
黄燕平,博士,主治医师,研究方向:泌尿男科学,E-mail:hyppin@163.com
纸质出版日期:2022-11-20,
收稿日期:2022-07-29,
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黄燕平,刘炜,张明等.男科门诊早泄患者的临床特征及影响因素[J].中山大学学报(医学科学版),2022,43(06):892-897.
HUANG Yan-ping,LIU Wei,ZHANG Ming,et al.The Clinical Characteristics and Influencing Factors of Premature Ejaculation in Andrology Outpatient Population[J].Journal of Sun Yat-sen University(Medical Sciences),2022,43(06):892-897.
黄燕平,刘炜,张明等.男科门诊早泄患者的临床特征及影响因素[J].中山大学学报(医学科学版),2022,43(06):892-897. DOI: 10.13471/j.cnki.j.sun.yat-sen.univ(med.sci).2022.0604.
HUANG Yan-ping,LIU Wei,ZHANG Ming,et al.The Clinical Characteristics and Influencing Factors of Premature Ejaculation in Andrology Outpatient Population[J].Journal of Sun Yat-sen University(Medical Sciences),2022,43(06):892-897. DOI: 10.13471/j.cnki.j.sun.yat-sen.univ(med.sci).2022.0604.
目的
2
分析男科门诊早泄(PE)患者的临床特征及影响因素。
方法
2
收集2020 年1 月至 2022 年5 月医院男科门诊20~60岁男性患者,详细记录一般人口学资料、病史、性生活史等,对符合要求的患者行早泄诊断量表(PEDT)、自我评估阴道内射精潜伏期(IELT)、国际勃起功能问卷-5(IIEF-5)、勃起硬度评分(EHS)、广泛性焦虑障碍量表(GAD-7)和健康问卷抑郁量表等量表评估。采用多元线性回归及Logistic回归分析PE的相关因素及独立危险因子。
结果
2
共纳入男科门诊患者973例,其中PE组445例(31.12±6.72)岁,非PE组528例(32.78±7.95)岁。两组间年龄、PEDT、IELT、IIEF-5、EHS、GAD-7及PHQ-9的差异均存在统计学意义(
P
<0.05)。回归分析校正后,PEDT与年龄(
b
=-0.11,
P
=0.001)、IIEF-5(
b
=-0.17,
P
<0.001)及PHQ-9(
b
=0.19,
P
<0.001)存在显著相关性。多因素校正后,年龄≤30岁、勃起功能障碍及抑郁状态三个变量有统计学意义(
P
<
0.01),其OR(95%CI)值分别为1.63(1.23, 2.16)、2.05(1.45,2.92)、1.90(1.37, 2.65)。
结论
2
PE与年龄、勃起功能评分、焦虑及抑郁评分等因素密切相关。年龄≤30岁、勃起功能障碍及抑郁状态是PE的独立危险因子。
Objective
2
To analyze the clinical characteristics and influencing factors of premature ejaculation (PE) in andrology outpatient population.
Methods
2
From January 2020 to May 2022, a total of 973 male subjects aged 20-60 years were enrolled in the andrology outpatient department of our hospital, and the subjects’ demographic data, medical history and sexual history were recorded in detail. Subjects with complete data were further evaluated by the Premature Ejaculation Diagnostic Tool (PEDT), self-estimated intra-vaginal ejaculation latency time (IELT), International Index of Erectile Function 5 (IIEF-5), Erectile Hardness Score (EHS), General Anxiety Disorder-7 (GAD-7) and Patients Health Questionnaire-9 (PHQ-9). Among the subjects, 445 cases (31.12±6.72 years old) were assigned to the PE group and 528 cases (32.78±7.95 years old) to the non-PE group based on their medical and sexual histories, and results of the evaluation. Multiple linear regression and Logistic regression were used to analyze the correlation factors and independent risk factors of PE.
Results
2
There were significant differences in the indicators including age, PEDT, IELT, IIEF-5, EHS, GAD-7 and PHQ-9 between the two groups (
P
<
0.05). Linear regression analysis showed that PEDT was significantly correlated with age (adjusted
b
=-0.11,
P
=0.001), IIEF-5 (adjusted
b
=-0.17,
P
<
0.001) and PHQ-9 (adjusted
b
=0.19,
P
<
0.001). After multivariate adjustment of Logistic regression, the variables such as age ≤30 years, erectile dysfunction and depression status were the independent risk factors for PE, and their Odds Ratio(OR) (95%CI) were 1.63(1.23, 2.16), 2.05(1.45,2.92) and 1.90(1.37, 2.65), respectively.
Conclusions
2
PE significantly correlates with age, erectile function scale scores, anxiety and depression scale scores. Age ≤30 years, erectile dysfunction and depression status are the independent risk factors for PE.
早泄勃起功能障碍焦虑抑郁
premature ejaculationerectile dysfunctionanxietydepression
Laumann EO, Paik A, Rosen RC. Sexual dysfunction in the United States: prevalence and predictors[J]. JAMA, 1999, 281(6): 537-544.
Salonia A, Bettocchi C, Boeri L, et al. European Association of Urology Guidelines on Sexual and Reproductive Health-2021 Update: male sexual dysfunction [J]. Eur Urol, 2021, 80(3): 333-357.
Huang YP, Chen B, Ping P, et al. The premature ejaculation diagnostic tool (PEDT): linguistic validity of the Chinese version[J]. J Sex Med, 2014, 11(9): 2232-2238.
Althof SE, Mcmahon CG, Waldinger MD, et al. An update of the International Society of Sexual Medicine's Guidelines for the diagnosis and treatment of premature ejaculation (PE)[J]. Sex Med, 2014, 2(2): 60-90.
Löwe B, Decker O, Müller S, et al. Validation and standardization of the Generalized Anxiety Disorder Screener (GAD-7) in the general population[J]. Med Care, 2008, 46(3): 266-274.
Negeri ZF, Levis B, Sun Y, et al. Accuracy of the Patient Health Questionnaire-9 for screening to detect major depression: updated systematic review and individual participant data meta-analysis[J]. BMJ, 2021, 375: n2183.
Mulhall JP, Goldstein I, Bushmakin AG, et al. Validation of the erection hardness score[J]. J Sex Med, 2007, 4(6): 1626-1634.
Rosen R, Cappelleri J, Smith M, et al. Development and evaluation of an abridged, 5-item version of the International Index of Erectile Function (IIEF-5) as a diagnostic tool for erectile dysfunction[J]. Int J Impot Res, 1999, 11(6): 319-326.
Xi Y, Colonnello E, Ma G, et al. Validity of Erectile Function Assessment Questionnaires in premature ejaculation patients: a comparative study between the abridged forms of the International Index of Erectile Function and proposal for optimal cutoff redefinition[J]. J Sex Med, 2021, 18(3): 440-447.
Tang Y, Wang Y, Zhu H, et al. Bias in evaluating erectile function in lifelong premature ejaculation patients with the International Index of Erectile Function-5[J]. J Sex Med, 2015, 12(10): 2061-2069.
Porst H, Montorsi F, Rosen RC, et al. The Premature Ejaculation Prevalence and Attitudes (PEPA) survey: prevalence, comorbidities, and professional help-seeking[J]. Eur Urol, 2007, 51(3): 816-823; discussion 824.
Gao J, Peng D, Zhang X, et al. Prevalence and associated factors of premature ejaculation in the Anhui male population in China: evidence-based unified definition of lifelong and acquired premature ejaculation[J]. Sex Med, 2017, 5(1): e37-e43.
Zhang X, Gao J, Liu J, et al. Distribution and factors associated with four premature ejaculation syndromes in outpatients complaining of ejaculating prematurely[J]. J Sex Med, 2013, 10(6): 1603-1611.
Corona G, Rastrelli G, Limoncin E, et al. Interplay between premature ejaculation and erectile dysfunction: a systematic review and meta-analysis[J]. J Sex Med, 2015, 12(12): 2291-2300.
Althof SE, Abdo CH, Dean J, et al. International Society for Sexual Medicine's guidelines for the diagnosis and treatment of premature ejaculation[J]. J Sex Med, 2010, 7(9): 2947-2969.
王怀鹏, 王行环, 古维灿, 等. 522例早泄患者的勃起功能调查[J]. 中华男科学, 2004, 10(1): 15-17.
Wang HP, Wang XH, Gu JC, et al.The investigation of erectile function in 522 patients with premature ejaculation[J]. Natl J Androl, 10(1): 15-17.
Chin CW, Tsai CM, Lin J-T, et al. A Cross-sectional observational study on the coexistence of erectile dysfunction and premature ejaculation[J]. Sex Med, 2021, 9(6): 100438.
Rastrelli G, Cipriani S, Corona G, et al. Clinical characteristics of men complaining of premature ejaculation together with erectile dysfunction: a cross-sectional study[J]. Andrology, 2019, 7(2): 163-171.
Tsai WK, Chiang PK, Lu CC, et al. The Comorbidity Between Premature Ejaculation and Erectile Dysfunction-A Cross-Sectional Internet Survey[J]. Sex Med, 2019, 7(4): 451-458.
Yang Y, Lu Y, Song Y, et al. Correlations and stratification analysis between premature ejaculation and psychological disorders[J]. Andrologia, 2019, 51(8): e13315.
Liu T, Jia C, Peng YF, et al. Correlation between premature ejaculation and psychological disorders in 270 Chinese outpatients[J]. Psychiatry Res, 2019, 272: 69-72.
Verze P, Arcaniolo D, Imbimbo C, et al. General and sex profile of women with partner affected by premature ejaculation: results of a large observational, non-interventional, cross-sectional, epidemiological study (IPER-F)[J]. Andrology, 2018, 6(5): 714-719.
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